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Treatment Options in Knee Osteoarthritis: The Patient's Perspective

One hundred patients with symptomatic knee osteoarthritis completed a questionnaire to measure the effect of specific medication characteristics (including administration, risks, benefits, and cost) on their choice of medication, and the percentage of patients preferring NSAIDs, COX-2 inhibitors, glucosamine and/or chondroitin sulfate, opioid derivatives, and capsaicin across different risks, benefits, and costs. Results showed that adverse events dominate in the choice of medication over effectiveness. Total capsaicin was preferred over other choices, with NSAIDS the least chosen option. Fraenkel L, Bogardus ST Jr, Concato J, et al. Archives of Internal Medicine. 28;164(12):1299-304, 2004.



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