This study done at Case Western Reserve University looked at the antioxidant
effects of Pomegranate extract in lab tests where it cut levels of an
inflammatory chemical called interleukin-1b and an enzyme that erodes
cartilage. The results show the potential of pomegranate fruit extract
to inhibit cartilage degradation that occurs in osteoarthritis and to
maintain joint integrity and function. Future studies are needed to
determine whether the fruit extract promotes cartilage repair and whether
it can also be effective in treatment rheumatoid arthritis. Ahmed S,
Wang N, Hafeez BB, et al. "Punica granatum L. Extract Inhibits
IL-1ß-Induced Expression of Matrix Metalloproteinases by Inhibiting
the Activation of MAP Kinases and NF- B in Human Chondrocytes In Vitro."
The Journal of Nutrition. 135:2096-2102, 2005.