An innovative combination of analgesics may hold the key to unlocking
neuropathic pain. In a study of over 300 patients, the benefits of combining
the strong opioid oxycodone with gabapentin produced a significant 33%
improvement on top of the best pain relief currently achievable using
the maximum tolerated dose of gabapentin alone for diabetic neuropathy.
The combination produced no additional side effects. Hanna M, O'Brien
C, Wilson, M. Neuropathic pain; optimising patient outcome with combination
therapy. Abstract Presentation at the European Federation of International
Association for the Study of Pain (IASP) Chapters (EFIC) 2006.